Molecular microbiologist position at Synthace

More info and to apply We require a molecular microbiologist, ideally experienced in the genetic manipulation of a diversity of microbial species.

We’re looking for someone who will thrive in a fast-paced and dynamic atmosphere, acting on their own initiative to solve complex problems. Candidates will need a PhD or equivalent experience and a strong track record of delivering high quality, quantitative results in a commercial or academic environment.

Synthace is committed to transforming the productivity of bioengineering through automation, computation and mathematics, so a willingness to work in a highly disciplinary environment and embrace cutting edge working practices is essential. Experience with automation or coding is an advantage.

SynthSys Mammalian Postdoc (closes 20 July)

More info at SynthSysEd website A highly motivated and talented Postdoctoral Research Associate is invited to join the laboratories of Dr. Abdenour Soufi and Prof. Susan Rosser at the University of Edinburgh to develop novel synthetic Biology tools for Cellular reprogramming applications. This is part of SynthSys Mammalian, which is a BBSRC/EPSRC/MRC Synthetic Biology Research Centre (SBRC), hosted by the School of Biological Sciences at the University of Edinburgh.

We are particularly interested in the interaction between transcription factors and chromatin during the conversion of human fibroblasts to induced pluripotent stem cells (iPSCs) (Soufi et al; Cell 2015, Soufi et al; Cell 2012). This collaborative project will focus on engineering synthetic transcription factors and will employ a wide range of techniques including; synthetic DNA-assembly and high-throughput-cloning, engineering synthetic transcription factors such as TALEs and ZFGs, human stem cell culture and lentivirus production, Next Generation Sequencing based techniques such as ChIP-seq, recombinant protein purification, DNA-protein interaction analysis such as EMSA and DNase-footprinting.

The successful candidate requires a PhD (or soon to be awarded) in an appropriate discipline with clear evidence of independent research capabilities. Knowledge and past experience in synthetic transcription factors, cellular reprogramming, stem cells and epigenetics are highly desirable.

The post is full-time for a fixed term of 3 years.

Junior Interdisciplinary Fellowship (Wellcome Trust/University of Cambridge - closes 22 July 2015)

Full details are available via the University of Cambridge.

The scheme is aimed at suitably qualified post-doctoral candidates with backgrounds in the physical sciences (incl. engineering, mathematics and computer sciences) who wish to gain experience in the application of their research to solve problems in the basic biological and biomedical sciences.

The fellowships are intended to provide opportunities for award holders to gain experience in applying biological approaches, and/or apply novel theoretical or experimental techniques from the physical sciences to address biological problems. In addition, it is hoped that this scheme will foster longer-term collaborations between Principal Investigators from the physical and life sciences disciplines within the University of Cambridge.

Research projects must fall within the broad remit of the Wellcome Trust. The research must be undertaken in laboratories within the School of the Biological Sciences or the School of Clinical Medicine.

Exceptionally, applications from post-doctoral candidates with a background in the life sciences wishing to gain experience working in the physical sciences may also be considered. However, this is not the core focus of the Scheme and it is expected that the host lab has a proven track record of life/physical sciences interdisciplinary research. A non-exclusive list of such labs can be found here: http://www.physbio.group.cam.ac.uk/members.html.

KTN: Synthetic Biology Special Interest Group Lead (closes 19 June 2015)

The Knowledge Transfer Network is a non-profit organisation that is funded by Innovate UK to be the UK’s innovation network across a wide range of sectors. Our main role is to bring together businesses, entrepreneurs, academics and funders to develop new products, processes and services. We are looking for an enthusiastic individual to join our team to deliver the strategy and activities of the synthetic biology special interest group which was set up to help translate the world-leading research in the UK into commercial applications and to deliver the key recommendations of a strategic roadmap.

More info on the position via the KTN Jobs site

Research Associate/Fellow – Mathematical/Computational Modelling, Nottingham SBRC (closes 18 June 2015)

The aim of the post is to provide research support for the BBSRC/EPSRC Synthetic Biology Research Centre (SBRC) in the creation and exploitation of gas fermenting microbial chassis as it relates to the sustainable production of chemicals and fuels.  SBRC Nottingham is one of three UK centres created by the BBSRC/EPSRC in 2014 and has received £14.3M in funding for a 5 year period. We are recruiting exceptional post-doctoral researchers to join the modelling and analysis team. The team will conduct cutting edge research into novel computational and mathematical modelling and analysis approaches and development of an integrated software suite to facilitate the rapid development of microbial chassis able to produce a range of platform chemicals. We seek individuals who will focus on biochemical/synthetic biology modelling, whose responsibilities will include development of synthetic biology devices and modelling of biochemical pathways. More info from jobs.ac.uk