Two positions are available in the laboratory of Professor Dek Woolfson, University of Bristol

For more information on the Woolfson group see: http://www.chm.bris.ac.uk/org/woolfson/index.html

For informal enquiries please contact: d.n.woolfson@bristol.ac.uk

Senior Research Associate / Research Associate in Protein Design for Biotechnology

http://www.jobs.ac.uk/job/BIT158/senior-research-associate-research-associate-in-protein-design-for-biotechnology/

A position for a postdoctoral research associate is available to work on a protein design in biotechnology project in the laboratory of Professor Dek Woolfson. The group is internationally leading in the development of protein design for applications in chemical and synthetic biology. The successful applicants will join a vibrant research team that combines bioinformatics and computational design, peptide and protein chemistry, biophysics and structural biology, and cell biology. Expertise in peptide chemistry and biophysical methods would be a distinct advantage for this particular post, and applicants from these areas are particularly encouraged to apply. However, we are keen to receive applications from ambitious and energetic individuals across the chemical and biochemical sciences or bioengineering with an interest in advancing protein design and its applications generally.

This post in protein design for biotechnology is for one year, and it is funded by a European Research Council Proof-of-Concept grant. The project will explore the use of a-helical barrels recently discovered and developed in the Woolfson lab (Thomson et al. (2014) Science 346:485-488) in the area of biosensing. Researchers with a background in peptide chemistry, surface chemistry and/or fluorescence spectroscopy/microscopy are strongly encouraged to apply. An active interest in driving the translation of this basic research into biotechnology applications of societal benefit would be an advantage.

Senior Research Associate / Research Associate in Protein Design

http://www.jobs.ac.uk/job/BIP002/senior-research-associate-research-associate-in-protein-design

A position for a postdoctoral research associate is available to work on protein design in the laboratory of Professor Dek Woolfson. The group is internationally leading in the development of protein design for applications in chemical and synthetic biology. The successful applicant will join a vibrant research team that combines bioinformatics and computational design, peptide and protein chemistry, biophysics and structural biology, and cell biology. Expertise in computational biochemistry and/or structural biology would be a distinct advantage for this post, and applicants from these areas are particularly encouraged to apply. However, we are keen to receive applications from ambitious and energetic individuals across the chemical and biochemical sciences or bioengineering with an interest in advancing protein design and its applications generally.

The post is available for an initial two-year period and is extendable to a further two years upon a successful start to the project. This is funded by a grant from the Biotechnology and Biological Research Council of the UK. The post-holder would be joined in year 2 by an expert in machine learning and virtual reality (VR) working in the laboratory of Dr David Glowacki (Chemistry, Bristol). Together, these two post-doctoral research associates will develop VR methods to aid and advance the computational design of completely new proteins building on research programmes across the two labs (Thomson et al. (2014) Science 346:485-488; Wood et al. (2017) Bioinformatics 33:3043-3050; https://arxiv.org/pdf/1801.02884.pdf). There will also be considerable opportunity to work with the international experimental and computational protein design and engineering communities.