DEPARTMENT/LOCATION: Department of Plant Sciences
SALARY: £32,236-£39,609
REFERENCE: PD17760
CATEGORY: Research
PUBLISHED: 10 June 2019
CLOSING DATE: 9 July 2019
A position is open for a Leverhulme Trust-funded postdoctoral research associate based within the Department of Plant Sciences at the University of Cambridge, and supervised by Professor Beverley Glover and Professor Alex Webb.
The appointee will investigate the evolution of the WDR proteins TTG1, LWD1 and LWD2. WDR proteins form a scaffold which supports the interaction of transcription factors, allowing the regulation of diverse suites of downstream genes. Our project aims to compare TTG1 and LWD protein function and identify changes important for their functional specificity. We aim to use mutant analyses to define biological function, in combination with yeast 2-hybrid analyses to determine which proteins are involved in the interacting complexes specifying different outcomes. RNAseq and ChIPseq will be used to establish the downstream targets resulting from the activities of these protein complexes.
We are looking for a highly motivated post-doctoral scientist to work in this area. The successful candidate must be able to demonstrate a strong background in the molecular genetic analysis of Arabidopsis, including a PhD in a relevant area. Experience with some of: mutant analysis, microscopy, RNAseq and ChIPseq will be necessary. Prior experience of yeast 2-hybrid analyses and/or circadian analyses will also be an advantage.
Fixed-term: The funds for this post are available for 3 years in the first instance.
Further information: http://www.jobs.cam.ac.uk/job/19960/